Known Issues for Adobe Media Encoder
No known issues
Rendering using Media Encoder conflicts with CUDA driver in MacOS (AME CC 2014 / 2015, and possible other versions, until AME CC 2015.1)
If the following conditions are met:
1. A composition is sent from AE or Premiere to AME for rendering;
2. That composition involves Neat Video;
3. The CUDA driver is installed,
then aerender may fail to load the composition and fail to start rendering.
This problem seems to be caused by a bug in AME itself. It has been reported to Adobe and confirmed.
A possible workaround is to open Neat Video v4 (or newer) in the main host application (AE or Premiere), go to its menu Tools > Preferences > Performance > GPU Troubleshooting, and disable NVIDIA GPU support. After restarting the host application, it should be possible to render the composition in AME.
Update: AME CC 2015.1 seems to fix this problem.